Tasigna drug interactions
Tasigna drug interactions
Your risk may be higher if you also use certain other medicines for infections, asthma, heart problems, high blood pressure, depression, mental illness, cancer, malaria, or HIV. In CML, the body produces abnormal white blood cells. Interactions Enter a drug name and nilotinib All Interactions Sort By: Contraindicated (12) arsenic trioxide disopyramide goserelin ibutilide indapamide leuprolide pentamidine pimozide procainamide. In a drug interaction study, the AUC value of nilotinib was decreased by about 80% following the addition of rifampicin/rifampin 600 mg once daily for 12 days.. The absence of an interaction does not necessarily mean no interactions exist. 8 USE IN SPECIFIC POPULATIONS 8. 4 Drugs that Inhibit Drug Transport Systems. This may increase your chances for serious and life-threatening side effects. Avoid taking other medicines or supplements with Tasigna that can also cause QTc prolongation. Find everything you need to know about Tasigna, including what it is used for, warnings, reviews, side effects, and interactions. Com The most dangerous interactions can cause an abnormal heart rhythm due to the prolongation of the QT interval. Brand Names Include: Tasigna Oral. All generic drug interactions for nilotinib oral (lists will include brand and generic names): 15 contraindicated drug interactions. Nilotinib (Tasigna®) is used to treat adult and pediatric patients greater than or equal to 1 year of age with chronic myeloid leukemia (CML) that is Philadelphia chromosome–positive (Ph+). Medications known to have serious interactions with nilotinib oral. Correct electrolyte abnormalities prior to initiating Tasigna and. Many drugs can interact with nilotinib. Interactions Drug Interactions This information should not be interpreted without the help of a healthcare provider. Tasigna can interact with many medicines and supplements and increase your chance for serious and life-threatening side effects. Correct electrolyte abnormalities prior to initiating Tasigna and monitor periodically during therapy.. Tasigna can cause a serious heart problem. , doctor or pharmacist) for more in formation. Nilotinib is a CYPA4 substrate and rifampin is a strong CYP3A4 inducer. Gleevec is an oral tyrosine kinase inhibitor that may be used to treat Ph+CML, Ph+ALL, and some other conditions. Tasigna may also be used for purposes not listed in this medication tasigna drug interactions guide. The most commonly reported nonhematologic adverse reactions (≥20%) in adult and pediatric patients receiving TASIGNA were nausea, rash, headache, fatigue, pruritus, vomiting, diarrhea, cough, constipation, arthralgia, nasopharyngitis, pyrexia, and night sweats.. Drug Interactions: TASIGNA can interact with many medicines and supplements. Grapefruit and certain herbal supplements (such as St. Tasigna disease interactions There are 8 disease interactions with Tasigna (nilotinib) which include: pancreatitis QT prolongation cardiovascular disease fluid retention bone marrow suppression electrolyte abnormalities hepatic impairment lactose intolerance Report options Share by QR Code. 6) Electrolyte Abnormalities: Tasigna can cause hypophosphatemia, hypokalemia, hyperkalemia, hypocalcemia, and hyponatremia. 3 Drugs that Affect Gastric pH 7. Approved Vet approved Nutraceutical Illicit Withdrawn. Coadministration of certain drugs may need to be avoided or dosage adjustments may be necessary; review drug interactions Find everything you need to know about Tasigna, including what it is used for, warnings, reviews, side effects, and interactions. 6) Electrolyte abnormalities: Tasigna can cause hypophosphatemia, hypokalemia, hyperkalemia, hypocalcemia, and hyponatremia. Drug interactions checker serious interactions for nilotinib oral. Coadministration of these drugs may lead to reduced nilotinib efficacy. Coadministration of certain drugs may need to be avoided or dosage adjustments may be necessary; review drug interactions The most dangerous interactions can cause an abnormal heart rhythm due to the prolongation of the QT interval. Com 230 mg/m2 orally twice daily (approximately 12 hours apart) on an empty stomach until disease progression or unacceptable toxicity. This includes prescription and over-the-counter medicines, vitamins, and herbal products 1 interaction. John’s Wort) can also affect how the drug works in the body.